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CD4/CD25 Mouse anti-Human, FITC, PE, eBioscience™

Antibody Cocktail

Brand:  Affymetrix eBioscience 22-8425-71

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15568316

  • £103.00 / 25 tests


Estimated Shipment date
from Supplier 26-03-2020
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Description

Description

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein-1 (pgp-1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non-hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. CD25: IL2 receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Specifications

Specifications

CD4/CD25
Cocktail
20 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P01589, P01730
CD4 antigen (p55); CD4 antigen p55; CD4 receptor; IL-2 receptor subunit alpha; IL-2R alpha; IL-2R alpha chain; IL-2R subunit alpha; IL2 RA antibody; Il2ra antibody; Interleukin 2 receptor alpha chain antibody; interleukin 2 receptor, alpha; T-cell surface antigen T4/Leu-3; TAC antigen; TAC antigen antibody
Mouse
Affinity chromatography
RUO
Antibody
3559, 920
Flow Cytometry
RPA-T4, BC96
FITC, PE
CD4
Liquid
CD4, IL2RA
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
Human
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For Research Use Only.