CD3e Golden Syrian Hamster, APC-eFluor 780, Clone: eBio500A2, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-0033-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15599486

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Regulatory Status RUO
Quantity 25μg
Conjugate APC-eFluor 780
Gene Alias CD3 epsilon
Antigen CD3e
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Applications Flow Cytometry
Host Species Golden Syrian Hamster
Isotype IgG
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone eBio500A2 (500A2)
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Concentration 0.2mg/mL
Format Conjugated

The eBio500A2 monoclonal antibody reacts with the 25 kD epsilon subunit of the mouse CD3 complex. CD3 subunits gamma, delta and epsilon are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells, as well as NKT cells. Binding of eBio500A2 to CD3 initiates the intracellular biochemical pathway resulting in cellular activation and proliferation. The 500A2 antibody is able to partially cross-block the 17A2 and 145-2C11 antibodies, indicating that all three of these anti-CD3 antibodies recognize distinct but overlapping epitopes.