CD3e Armenian Hamster anti-Mouse, FITC, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0031-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15287979

Quantity Price
1 £ 158.36 / 500µg
EU Stock 7
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Description and Specification

Specification

Antigen CD3e
Format Conjugated
Gene Alias CD3 epsilon
Primary or Secondary Primary
Conjugate FITC
Clone 145-2C11
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Quantity 500μg
Host Species Armenian Hamster
Isotype IgG
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.