CD3e Armenian Hamster anti-Mouse, Clone: 145-2C11, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0031-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15248337

Quantity Price
1 £ 48.31 / 50µg
EU Stock 15
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Description and Specification

Specification

Format Purified
Applications Flow Cytometry
Applications Functional Assay
Isotype IgG
Conjugate Unlabeled
Formulation aqueous buffer, no sodium azide
Antigen CD3e
Primary or Secondary Primary
Clone 145-2C11
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Quantity 50μg
Storage Requirements Store at 2-8°C.
Species Reactivity Mouse
Regulatory Status RUO
Gene Alias CD3 epsilon

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.