CD3e Armenian Hamster anti-Mouse, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0031-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15507416

Quantity Price
1 £ 42.19 / 100µg
EU Stock 3
Add to basket


Description and Specification

Specification

Storage Requirements Store at 2-8°C.
Format Purified
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Clone 145-2C11
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Antigen CD3e
Quantity 100μg
Gene Alias CD3 epsilon
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Regulatory Status RUO
Host Species Armenian Hamster
Isotype IgG
Conjugate Unlabeled

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.