CD3e Armenian Hamster anti-Mouse, Biotin, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0031-86

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15259399

Quantity Price
1 £ 268.40999999999997 / 1mg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze.
Quantity 1mg
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Applications Flow Cytometry
Isotype IgG
Antigen CD3e
Conjugate Biotin
Concentration 0.5mg/mL
Clone 145-2C11
Gene Alias CD3 epsilon
Primary or Secondary Primary
Format Conjugated

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.