CD3e Armenian Hamster anti-Mouse, Biotin, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0031-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15249399

Quantity Price
1 £ 146.13 / 500µg
EU Stock 16
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Description and Specification

Specification

Host Species Armenian Hamster
Format Conjugated
Clone 145-2C11
Gene Alias CD3 epsilon
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze.
Isotype IgG
Conjugate Biotin
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Applications Flow Cytometry
Primary or Secondary Primary
Quantity 500μg
Species Reactivity Mouse
Antigen CD3e
Regulatory Status RUO

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.