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CD39 Rat anti-Mouse, PerCP-eFluor 710, Clone: 24DMS1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-0391-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15361250

  • £115.67 / 25µg


Estimated Shipment
04-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI. E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP. CD39 is the dominant member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation. CD39 can impact expression of CD73, another E-NTPase. Together, these molecules influence inflammation responses. CD39 is expressed on B cells, Langerhans cells and most monocytes. In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells. T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo.
Description & Specifications

Specifications

CD39
24DMS1
PerCP-eFluor 710
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
Conjugated
Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
IgG2b
RUO
Primary
Murine