CD39 Rat anti-Mouse, PE-Cy7, Clone: 24DMS1, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0391-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15320920

Quantity Price
1 £ 111.78 / 25µg
EU Stock 4
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Description and Specification

Specification

Applications Flow Cytometry
Isotype IgG2b
Primary or Secondary Primary
Species Reactivity Mouse
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Host Species Rat
Concentration 0.2mg/mL
Antigen CD39
Regulatory Status RUO
Clone 24DMS1
Quantity 25μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
Conjugate PE-Cy7
Monoclonal or Polyclonal Monoclonal

The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI. E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP. CD39 is the dominant member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation. CD39 can impact expression of CD73, another E-NTPase. Together, these molecules influence inflammation responses. CD39 is expressed on B cells, Langerhans cells and most monocytes. In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells. T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo.