CD38 Rat anti-Mouse, PE-Cy5, Clone: 90, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 15-0381-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15380470

Quantity Price
1 £ 109.45 / 50µg
EU Stock 1
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Description and Specification

Specification

Host Species Rat
Primary or Secondary Primary
Conjugate PE-Cy5
Isotype IgG2a
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Antigen CD38
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 50μg
Regulatory Status RUO
Clone 90
Format Conjugated
Species Reactivity Mouse
Concentration 0.2mg/mL

The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ∽42kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.