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CD38 Rat anti-Mouse, eFluor 450, Clone: 90, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-0381-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15371710

  • £61.11 / 25µg


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ∽42kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.
Specifications

Specifications

CD38
90
eFluor 450
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
IgG2a
RUO
Primary
Murine