CD38 Rat anti-Mouse, eFluor 450, Clone: 90, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0381-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15371710

Quantity Price
1 £ 61.11 / 25µg
EU Stock 2
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Description and Specification

Specification

Applications Flow Cytometry
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Quantity 25μg
Species Reactivity Mouse
Host Species Rat
Antigen CD38
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Isotype IgG2a
Format Conjugated
Clone 90
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Conjugate eFluor 450

The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ∽42kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.