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CD38, clone: 90, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0381-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15216927

  • £68.51 / 100µg


Estimated Shipment
28-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ∽42kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.Applications Reported: The 90 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining. It has also been reported in functional assays. (Please use Functional Grade purified 90, cat. 16-0381, in functional assays.).Applications Tested: The 90 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD38
90
Unconjugated
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Immunohistochemistry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
IgG2a
RUO
Primary
Murine
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