CD38 Mouse anti-Rat, eFluor 660, Clone: 14.27, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-0380-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15569876

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Conjugate eFluor 660
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Format Conjugated
Primary or Secondary Primary
Species Reactivity Rat
Quantity 25μg
Gene Alias ADP-ribosyl cyclase 1
Concentration 0.2mg/mL
Clone 14.27
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Isotype IgG2b
Antigen CD38
Host Species Mouse

The monoclonal antibody 14.27 reacts with rat CD38, also known as ADP-ribosyl cyclase. CD38 is a type II transmembrane glycoprotein that is an ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic adenosine diphosphate ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP). cADPR and NAADP are secondary messengers involved in calcium mobilization. CD38 can also act as a receptor for CD31 or agonist monoclonal antibodies. CD38 is expressed by leukocytes, early hematopoietic precursor cells, epithelial cells, astrocytes, some muscle cells, kidney cells, and thyroid cells. CD38 plays a role in the production of pro-inflammatory cytokines, proliferation, cell activation, cell migration, cell adhesion, and protection from apoptosis.