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CD38 Mouse anti-Rat, eFluor® 660, Clone: 14.27, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-0380-80

Code : NEW

Additional Details : Weight : 0.09500kg

Product Code. 15569876

  • £57.75 / 25µg

Estimated Shipment
05-10-2020

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Description

Description

eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, maligt lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter’s Syndrome.
Specifications

Specifications

CD38
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q64244
T10, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, CD38 antigen p45, NAD+ nucleosidase, cADPr hydrolase 1, cyclic ADP-ribose hydrolase 2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Rat
Flow Cytometry
14.27
eFluor™ 660
Cd38
Liquid
Cd38
IgG2b, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
25668
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For Research Use Only.