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CD38 Mouse anti-Human, PerCP-eFluor 710, Clone: HB7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-0388-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15529116

  • £212.40 / 100 tests


EU Stock 7
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Disclaimers:

For Research Use Only.


Description

Description

The HB7 monoclonal antibody reacts with the human CD38 molecule, an approximately 45kDa type II transmembrane protein. CD38 is an ectoenzyme which catalyses NAD into nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR), both of which are secondary messengers. Expression of CD38 is bimodal during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Additionally CD38 is found in a variety of tissues and other hematopoietic cells (e.g. T cells, NK cells and monocytes) and can be used to phenotype leukemias and monitor HIV-1 progression. The CD34+CD38- population of hematopoietic stems cells is thought to define the most pluripotent cells (e.g. blast colony forming cells). In addition to surface expression, CD38 has recently been found in the nucleus where it may play a role in monitoring calcium levels.
Specifications

Specifications

CD38
HB7
PerCP-eFluor 710
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.06μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
IgG1
RUO
Primary
Human