CD37 Mouse anti-Human, APC, Clone: MB-1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0379-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15507926

Quantity Price
1 £ 164.47 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Antigen CD37
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate APC
Format Conjugated
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100 tests
Isotype IgG1
Clone MB-1
Gene Alias gp40-52
Regulatory Status RUO
Concentration 5μL (0.06μg)/test
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Species Reactivity Human

This MB-1 monoclonal antibody recognizes human CD37. This tetraspanin is expressed on mature B cells, but not on pro-B or plasma cells. CD37 is also weakly expressed on T cells, monocytes, neutrophils, dendritic cells, and macrophages. This cell surface glycoprotein is not detected on NK cells, platelets, or erythrocytes. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 reportedly associates with MHC class II, CD19, CD21, and other members of the tetraspanin family. CD37 has been implicated in signal transduction, B cell activation, and T cell proliferation. CD37 has been used as a therapeutic target for treating B cell malignancies.