CD37 Mouse anti-Human, APC, Clone: MB-1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0379-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15597916

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Primary or Secondary Primary
Concentration 5μL (0.06μg)/test
Quantity 25 tests
Isotype IgG1
Conjugate APC
Gene Alias gp40-52
Antigen CD37
Clone MB-1
Applications Flow Cytometry
Host Species Mouse
Regulatory Status RUO
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal

This MB-1 monoclonal antibody recognizes human CD37. This tetraspanin is expressed on mature B cells, but not on pro-B or plasma cells. CD37 is also weakly expressed on T cells, monocytes, neutrophils, dendritic cells, and macrophages. This cell surface glycoprotein is not detected on NK cells, platelets, or erythrocytes. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 reportedly associates with MHC class II, CD19, CD21, and other members of the tetraspanin family. CD37 has been implicated in signal transduction, B cell activation, and T cell proliferation. CD37 has been used as a therapeutic target for treating B cell malignancies.