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CD37, APC, clone: MB-1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0379-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15597916

  • £68.96 / 25 tests


Estimated Shipment date
from Supplier 30-07-2018
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Description

Description

Description: This MB-1 monoclonal antibody recognizes human CD37. This tetraspanin is expressed on mature B cells, but not on pro-B or plasma cells. CD37 is also weakly expressed on T cells, monocytes, neutrophils, dendritic cells, and macrophages. This cell surface glycoprotein is not detected on NK cells, platelets, or erythrocytes. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 reportedly associates with MHC class II, CD19, CD21, and other members of the tetraspanin family. CD37 has been implicated in signal transduction, B cell activation, and T cell proliferation. CD37 has been used as a therapeutic target for treating B cell malignancies.Applications Reported: This MB-1 antibody has been reported for use in flow cytometric analysis.Applications Tested: This MB-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD37
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P11049
Cluster designation 37
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MB-1
APC
CD37
Conjugated
CD37
IgG1, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
951
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