CD369 (Clec7A, Dectin-1) Mouse anti-Human, Non-human primate, PE, Clone: 15E2, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9856-41

25TEST Anti-Human/Non-Human Primate CD369 (Clec7a, Dectin-1) PE

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15597246

Quantity Price
1 £120.20 / 25 tests
Estimated Shipment date
from Supplier 31-10-2016
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Description and Specification


Antigen CD369 (Clec7A, Dectin-1)
Applications Flow Cytometry
Clone 1.50E+03
Concentration 5μL (0.25μg)/test
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Beta-glucan receptor, ClecSF12
Host Species Mouse
Isotype IgG2a
Quantity 25 tests
Regulatory Status RUO
Species Reactivity Human, Non-human primate
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This 15E2 monoclonal antibody reacts with human and non-human primate CD369, which is also known as the Dectin-1 or beta-glucan receptor or CLEC7A. CD369 is expressed predominantly on monocytes, macrophages, and dendritic cells. Moreover, this receptor can also be detected on neutrophils and lymphocytes, as well as induced by cytokines such as IL-4 or LPS. In humans, CD369 exists as two isoforms that arise due to alternative splicing. CD369 binds beta-1,3-glucan and plays an important role in activating signal transduction involved in the innate immune response to fungal and mycobacterial infections. Studies have also shown the involvement of CD369 in dendritic cell activation.

The 15E2 monoclonal antibody has been reported to recognize both isoforms of CD369 and activate dendritic cells. It does not crossreact to mouse CD369.