CD368 (Clec6) Mouse anti-Human, eFluor 660, Clone: 9B9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9113-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15550077

Quantity Price
1 £ 78.88 / 25 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Gene Alias CLEC4D, CLECSF8
Clone 9B9
Conjugate eFluor 660
Format Conjugated
Antigen CD368 (Clec6)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Isotype IgG2b
Concentration 5μL (0.5μg)/test
Applications Flow Cytometry
Species Reactivity Human
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Host Species Mouse

This 9B9 monoclonal antibody reacts with human CD368, also known as Clec6 or ClecsF8 or Clec4D. In peripheral blood, this C-type lectin is expressed highly on granulocytes and CD14+CD16- monocytes. Some dendritic cell populations also exhibit low levels of CD368 expression. Studies have demonstrated that this receptor undergoes endocytosis due to its C-type lectin-like domain. CD368 functions as a phagocytic receptor and is involved in proinflammatory cytokine production in cooperation with Toll-like receptors. Finally, CD368 also participates in cellular activation via signaling through Syk kinase.