CD368 (Clec6) Mouse anti-Human, eFluor 660, Clone: 9B9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9113-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15560077

Quantity Price
1 £ 195.05 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Clone 9B9
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Format Conjugated
Isotype IgG2b
Quantity 100 tests
Conjugate eFluor 660
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD368 (Clec6)
Concentration 5μL (0.5μg)/test
Gene Alias CLEC4D, CLECSF8
Species Reactivity Human

This 9B9 monoclonal antibody reacts with human CD368, also known as Clec6 or ClecsF8 or Clec4D. In peripheral blood, this C-type lectin is expressed highly on granulocytes and CD14+CD16- monocytes. Some dendritic cell populations also exhibit low levels of CD368 expression. Studies have demonstrated that this receptor undergoes endocytosis due to its C-type lectin-like domain. CD368 functions as a phagocytic receptor and is involved in proinflammatory cytokine production in cooperation with Toll-like receptors. Finally, CD368 also participates in cellular activation via signaling through Syk kinase.