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CD366 (TIM3) Monoclonal Antibody (F38-2E2), Super Bright™ 645, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£154.00 - £317.00

Specifications

Antigen CD366 (TIM3)
Clone F38-2E2
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15963644
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Affymetrix eBioscience
64-3109-41
25 Tests
£154.00
Pack of 25
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Estimated Shipment: 23-04-2024
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15973644
View Documents Promotion Details
Affymetrix eBioscience
64-3109-42
100 Tests
£317.00
Pack of 100
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Estimated Shipment: 16-04-2024
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Description

Description

Description: The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines. The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo. Applications Reported: This 29A1.4 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 29A1.4 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

CD366 (TIM3) Monoclonal antibody specifically detects CD366 (TIM3) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD366 (TIM3)
5 μL/Test
Monoclonal
Liquid
RUO
Q8TDQ0
IgG1 κ
Affinity chromatography
Antibody
F38-2E2
Flow Cytometry
Super Bright 645
Mouse
Human
84868
Primary
4° C, store in dark, DO NOT FREEZE!
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