CD365 (TIM1) Rat anti-Mouse, Biotin, Clone: RMT1-4, eBioscience™

Rat Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-5861-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg

Disclaimers: For Research Use Only.

Product Code. 15209879

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 05-06-2017
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Description and Specification


Antigen CD365 (TIM1)
Applications Flow Cytometry
Clone RMT1-4
Concentration 0.5mg/mL
Conjugate Biotin
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias HAVCR1, T cell immunoglobulin and mucin domain-containing protein 1
Host Species Rat
Isotype IgG2b
Quantity 50μg
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Murine

The RMT1-4 monoclonal antibody reacts with mouse CD365 (also known as TIM1 and HAVCR1) and is a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. CD365 has been found on activated CD4+ T cells, mast cells, and a subset of B cells. CD365 is involved in renal injury, tissue homeostasis, and T cell costimulation. CD365 promotes the differentiation of Th2 cells and the production of IL-4. CD365 can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself. CD365 and TIM4 can mediate uptake of apoptotic cells through recognition of phosphatidylserine. CD365, as well as the other TIM family members, are associated with susceptibility to atopic and autoimmune diseases. In humans, certain polymorphic variants of CD365 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV).