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CD36 Mouse anti-Human, PerCP-eFluor 710, Clone: eBioNL07 (NL07), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-0369-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15509116

  • £174.01 / 100 tests


Estimated Shipment date
from Supplier 27-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody eBioNL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is in the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 expression is broad and includes microvascular (but not large vessel) endothelium, adipocytes, skeletal muscle, dendritic cells, epithelia of the retina, breast, and intestine, smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and megakaryocytes. Expression on platelets is absent on Nak-a negative donors. Unlike other scavenger receptor, CD36 binds LDL that has been exposed to “minimally” oxidizing conditions. CD36 is also a fatty acid translocase (FAT) necessary for the transport of long-chain fatty acids (LCFAs) and therefore may play a role in atherosclerosis.
Specifications

Specifications

CD36
eBioNL07 (NL07)
PerCP-eFluor 710
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
GP IIIb, Thrombospondin Receptor
IgM
RUO
Primary
Human