CD36 Mouse anti-Human, Clone: eBioNL07 (NL07), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0369-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15286917

Quantity Price
1 £ 36.08 / 25µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Concentration 0.5mg/mL
Primary or Secondary Primary
Host Species Mouse
Species Reactivity Human
Gene Alias GP IIIb, Thrombospondin Receptor
Format Purified
Isotype IgM
Storage Requirements Store at 2-8°C.
Applications Flow Cytometry
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Antigen CD36
Regulatory Status RUO
Clone eBioNL07 (NL07)

The monoclonal antibody eBioNL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is in the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 expression is broad and includes microvascular (but not large vessel) endothelium, adipocytes, skeletal muscle, dendritic cells, epithelia of the retina, breast, and intestine, smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and megakaryocytes. Expression on platelets is absent on Naka negative donors. Unlike other scavenger receptor, CD36 binds LDL that has been exposed to “minimally” oxidizing conditions. CD36 is also a fatty acid translocase (FAT) necessary for the transport of long-chain fatty acids (LCFAs) and therefore may play a role in atherosclerosis.