CD36 Mouse anti-Human, Clone: eBioNL07 (NL07), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0369-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15296917

Quantity Price
1 £ 91.11 / 100µg
EU Stock 2
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Description and Specification

Specification

Host Species Mouse
Isotype IgM
Regulatory Status RUO
Concentration 0.5mg/mL
Quantity 100μg
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Gene Alias GP IIIb, Thrombospondin Receptor
Primary or Secondary Primary
Conjugate Unlabeled
Clone eBioNL07 (NL07)
Format Purified
Antigen CD36
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal

The monoclonal antibody eBioNL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is in the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 expression is broad and includes microvascular (but not large vessel) endothelium, adipocytes, skeletal muscle, dendritic cells, epithelia of the retina, breast, and intestine, smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and megakaryocytes. Expression on platelets is absent on Naka negative donors. Unlike other scavenger receptor, CD36 binds LDL that has been exposed to “minimally” oxidizing conditions. CD36 is also a fatty acid translocase (FAT) necessary for the transport of long-chain fatty acids (LCFAs) and therefore may play a role in atherosclerosis.