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CD357 (AITR/GITR) Monoclonal Antibody (DTA-1), Super Bright™ 600, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£310.00

Specifications

Antigen CD357 (AITR/GITR)
Clone DTA-1
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15913564
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Affymetrix eBioscience
63-5874-82
100 μg
£310.00
100µg
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Estimated Shipment: 15-04-2024
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Description

Description

Description: The DTA-1 monoclonal antibody reacts with mouse GITR, Glucocorticoid-Induced TNFR family gene, also known as TNFRSF18. In naive mice, GITR is expressed predomitly by CD4+CD25+ T regulatory cells (Treg) and by CD25+ CD4+ CD8- thymocytes. Stimulation of GITR with DTA-1 antibody abrogates Treg cell-mediated suppression. Although it does not deplete CD357 expressing cells in vivo, it has been shown to induce tumorogenesis. The removal of GITR-expressing Treg cells or the administration of DTA-1 resulted in organ specific autoimmune disease. Applications Reported: This DTA-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This DTA-1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.03 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Super Bright 600 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 600 nm. We recommend using a 610/20 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome.

CD357 (AITR/GITR) Monoclonal antibody specifically detects CD357 (AITR/GITR) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD357 (AITR/GITR)
0.2 mg/mL
Monoclonal
Liquid
RUO
O35714
Tnfrsf18
Primary
4° C, store in dark, DO NOT FREEZE!
Tnfrsf18
DTA-1
Flow Cytometry
Super Bright 600
Rat
Mouse
21936
IgG2b κ
Affinity chromatography
Antibody
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