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CD357 (AITR/GITR) Mouse anti-Human, PE, Clone: eBioAITR, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5875-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15557036

  • £174.09 / 100 tests


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody reacts with human AITR, Activation Inducible TNFR family member, an approximately 25kDa member of the TNFR superfamily. AITR mRNA is detected in lymph node, peripheral blood leukocytes and weakly in spleen. AITR mRNA expression was upregulated within 24 hour on PMA/ionomycin or PHA stimulated PBMC. At the protein level, AITR is expressed by a small population of activated PBMC. AITR associates with TRAF1, TRAF2 and TRAF3 and induces nuclear factor NF-κB activation via TRAF2. Recently TL6 (AITRL) has been reported as the ligand for AITR. Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells.
Specifications

Specifications

CD357 (AITR/GITR)
eBioAITR
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TNFRSF18, activation-inducible TNFR family member
IgG1
RUO
Primary
Human