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CD357 (AITR/GITR), APC, clone: eBioAITR, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5875-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15588146

  • £202.12 / 100 tests


EU Stock 4
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Description

Description

Description: The monoclonal antibody reacts with human AITR, Activation Inducible TNFR family member, an approximately 25kDa member of the TNFR superfamily. AITR mRNA is detected in lymph node, peripheral blood leukocytes and weakly in spleen. AITR mRNA expression was upregulated within 24 hour on PMA/ionomycin or PHA stimulated PBMC. At the protein level, AITR is expressed by a small population of activated PBMC. AITR associates with TRAF1, TRAF2 and TRAF3 and induces nuclear factor NF-kappaB activation via TRAF2. Recently TL6 (AITRL) has been reported as the ligand for AITR. Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells.Applications Reported: This eBioAITR antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioAITR antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (1 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD357 (AITR/GITR)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9Y5U5
AITR, GITR-D, TNFRSF18
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioAITR
APC
TNFRSF18
Conjugated
TNFRSF18
IgG1
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
8784
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