CD338 (ABCG2) Mouse anti-Human, PE, Clone: 5D3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-8888-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15517146

Quantity Price
1 £ 78.88 / 25 tests
EU Stock 2
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Description and Specification

Specification

Gene Alias Bcrp1, MXR
Regulatory Status RUO
Antigen CD338 (ABCG2)
Format Conjugated
Clone 5D3
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Isotype IgG2b
Quantity 25 tests
Concentration 0.2mg/mL; 5μL (0.25μg)/test
Conjugate PE
Applications Flow Cytometry
Host Species Mouse
Primary or Secondary Primary

The 5D3 monoclonal antibody reacts with the extracellular portion of the human ABCG2 protein, also known as Bcrp1 and MXR. The ABCG2 gene, a member of the multi-drug resistance (MDR) family, is highly expressed on primitive ‘side-population’ (SP) stem cells, which are defined by the efflux of fluorescent dyes such as Rhodamine 123 and Hoechest 33342. In the bone marrow, about 0.05% of cells display the low fluorescence and are highly enriched for repopulating cells. The SP cells, which express low or undetectable levels of CD34, have been identified in multiple species. In addition, expression of ABCG2 appears to be highly conserved.