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CD336 (NKp44) Monoclonal Antibody (44.189), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£101.00 - £289.00

Specifications

Antigen CD336 (NKp44)
Clone 44.189
Applications Flow Cytometry
Classification Monoclonal
Conjugate PerCP-eFluor 710
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15539246
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Affymetrix eBioscience
46-3369-42
100 Tests
£289.00
100 tests
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15529246
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Affymetrix eBioscience
46-3369-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The monoclonal antibody 44.189 reacts with human CD336, which is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation. The 44.189 antibody has been reported to facilitate CD336 crosslinking. Applications Reported: This 44.189 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 44.189 antibody has been pre-titrated and tested by flow cytometric analysis of IL-2-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

CD336 (NKp44) Monoclonal antibody specifically detects CD336 (NKp44) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD336 (NKp44)
Flow Cytometry
PerCP-eFluor 710
Mouse
Human
9436
IgG2b κ
Affinity chromatography
NCR2
44.189
Monoclonal
Liquid
RUO
O95944
NCR2
Primary
Antibody
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