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CD336 (NKp44) Monoclonal Antibody (44.189), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£101.00 - £289.00
Specifications
Antigen | CD336 (NKp44) |
---|---|
Clone | 44.189 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | PerCP-eFluor 710 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15539246
|
Affymetrix eBioscience
46-3369-42 |
100 Tests |
£289.00
100 tests |
Estimated Shipment: 03-05-2024 Log in to see stock. |
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15529246
|
Affymetrix eBioscience
46-3369-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The monoclonal antibody 44.189 reacts with human CD336, which is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation. The 44.189 antibody has been reported to facilitate CD336 crosslinking. Applications Reported: This 44.189 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 44.189 antibody has been pre-titrated and tested by flow cytometric analysis of IL-2-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
CD336 (NKp44) Monoclonal antibody specifically detects CD336 (NKp44) in Human samples. It is validated for Flow Cytometry.Specifications
CD336 (NKp44) | |
Flow Cytometry | |
PerCP-eFluor 710 | |
Mouse | |
Human | |
9436 | |
IgG2b κ | |
Affinity chromatography | |
NCR2 |
44.189 | |
Monoclonal | |
Liquid | |
RUO | |
O95944 | |
NCR2 | |
Primary | |
Antibody |
For Research Use Only.