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CD336 (NKp44) Mouse anti-Human, APC, Clone: 44.189, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-3369-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15538086

  • £72.77 / 25 tests


EU Stock 2
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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody 44.189 reacts with human CD336, which is also known as NKp44 or NCR2. CD336 is a 44kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.

The 44.189 antibody has been reported to facilitate CD336 crosslinking.
Specifications

Specifications

CD336 (NKp44)
44.189
APC
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25ugμg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
NCR2
IgG2b
RUO
Primary
Human