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CD335 (NKp46) Rat anti-Mouse, APC-eFluor 780, Clone: 29A1.4, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 47-3351-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15549586

  • £186.31 / 100µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines.

The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo.
Description & Specifications

Specifications

CD335 (NKp46)
29A1.4
APC-eFluor 780
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
NCR1, Ly-94
IgG2a
RUO
Primary
Murine