CD335 (NKp46) Mouse anti-Human, eFluor 450, Clone: 9E2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-3359-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599736

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Description and Specification

Specification

Quantity 25 tests
Primary or Secondary Primary
Host Species Mouse
Applications Flow Cytometry
Concentration 5μL (0.125μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Antigen CD335 (NKp46)
Clone 9.00E+02
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias NCR1, Ly-94
Species Reactivity Human
Conjugate eFluor 450

This 9E2 monoclonal antibody reacts with human CD335, which is also known as NKp46. Expressed on NK cells, CD335 is a member of the natural cytotoxicity receptor family that also includes NKp30 and NKp44. This type I transmembrane glycoprotein is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor and virus-infected (e.g., influenza) cells. CD335 also interacts with pancreatic beta cells during the development of type I diabetes.

The 9E2 antibody has been reported to induce cytotoxicity.