CD335 (NKp46) Mouse anti-Human, Clone: 9E2, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-3359-85

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15557786

Quantity Price
1 £ 243.96 / 500µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Species Reactivity Human
Isotype IgG1
Concentration 1mg/mL
Format Purified
Formulation aqueous buffer, no sodium azide
Host Species Mouse
Quantity 500μg
Primary or Secondary Primary
Antigen CD335 (NKp46)
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Clone 9.00E+02
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Monoclonal or Polyclonal Monoclonal
Gene Alias NCR1, Ly-94

This 9E2 monoclonal antibody reacts with human CD335, which is also known as NKp46. Expressed on NK cells, CD335 is a member of the natural cytotoxicity receptor family that also includes NKp30 and NKp44. This type I transmembrane glycoprotein is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor and virus-infected (e.g., influenza) cells. CD335 also interacts with pancreatic beta cells during the development of type I diabetes.

The 9E2 antibody has been reported to induce cytotoxicity.