CD335 (NKp46) Mouse anti-Human, Clone: 9E2, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-3359-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15547786

Quantity Price
1 £ 109.45 / 100µg
EU Stock 1
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Description and Specification

Specification

Antigen CD335 (NKp46)
Species Reactivity Human
Quantity 100μg
Format Purified
Applications Flow Cytometry
Applications Functional Assay
Gene Alias NCR1, Ly-94
Isotype IgG1
Clone 9.00E+02
Concentration 1mg/mL
Formulation aqueous buffer, no sodium azide
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Host Species Mouse
Primary or Secondary Primary

This 9E2 monoclonal antibody reacts with human CD335, which is also known as NKp46. Expressed on NK cells, CD335 is a member of the natural cytotoxicity receptor family that also includes NKp30 and NKp44. This type I transmembrane glycoprotein is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor and virus-infected (e.g., influenza) cells. CD335 also interacts with pancreatic beta cells during the development of type I diabetes.

The 9E2 antibody has been reported to induce cytotoxicity.