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CD335 (NKp46), Functional Grade, clone: 9E2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-3359-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15547786

  • £112.51 / 100µg


Estimated Shipment date
from Supplier 26-03-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: This 9E2 monoclonal antibody reacts with human CD335, which is also known as NKp46. Expressed on NK cells, CD335 is a member of the natural cytotoxicity receptor family that also includes NKp30 and NKp44. This type I transmembrane glycoprotein is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor and virus-infected (e.g., influenza) cells. CD335 also interacts with pancreatic beta cells during the development of type I diabetes.The 9E2 antibody has been reported to induce cytotoxicity.Applications Reported: This 9E2 antibody has been reported for use in flow cytometric analysis and to induce cytotoxicity in functional assays.Applications Tested: This 9E2 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

CD335 (NKp46)
9.00E+02
Unconjugated
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
NCR1, Ly-94
IgG1
RUO
Primary
Human
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