CD335 (NKp46) Mouse anti-Human, APC, Clone: 9E2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-3359-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15518086

Quantity Price
1 £ 72.77 / 25 tests
EU Stock 2
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Description and Specification

Specification

Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 9.00E+02
Concentration 5μL (0.125μg)/test
Gene Alias NCR1, Ly-94
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Quantity 25 tests
Antigen CD335 (NKp46)
Host Species Mouse
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Conjugate APC
Applications Flow Cytometry

This 9E2 monoclonal antibody reacts with human CD335, which is also known as NKp46. Expressed on NK cells, CD335 is a member of the natural cytotoxicity receptor family that also includes NKp30 and NKp44. This type I transmembrane glycoprotein is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor and virus-infected (e.g., influenza) cells. CD335 also interacts with pancreatic beta cells during the development of type I diabetes.

The 9E2 antibody has been reported to induce cytotoxicity.