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CD33 Monoclonal Antibody (9A11-CD33), PE-Cyanine7, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£98.75 - £268.00

Specifications

Antigen CD33
Clone 9A11-CD33
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
15548386
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Affymetrix eBioscience
25-0331-82
100 μg
£268.00
100µg
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15538386
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Affymetrix eBioscience
25-0331-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: This monoclonal antibody 9A11-CD33 reacts with mouse CD33, also known as Siglec3 and gp67. CD33 belongs to the sialic acid-binding immunoglobulin lectins (Siglec) family that binds to sialic acid-containing glycans on cell surface glycoproteins and glycolipids on mammalian cells. Mouse CD33 binds to short O-linked glycans of certain mucins and sialyl-Tn epitopes. Mouse CD33 is expressed by mature granulocytes, immature myeloid cells, and microglia. Unlike human CD33, mouse CD33 lacks a cytoplasmic ITIM domain and exists as two splice variants that have different cytoplasmic tails. In microglia, CD33 inhibits the phagocytosis of toxic amyloid beta. Applications Reported: This 9A11-CD33 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 9A11-CD33 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat.

CD33 Monoclonal antibody specifically detects CD33 in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD33
0.2 mg/mL
Monoclonal
Liquid
RUO
Q63994
IgG1 κ
Affinity chromatography
Antibody
9A11-CD33
Flow Cytometry
PE-Cyanine7
Rat
Mouse
12489
Primary
4° C, store in dark, DO NOT FREEZE!
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