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CD32b, APC, clone: AT130-2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0321-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15597906

  • £186.79 / 100µg


EU Stock 2
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Description

Description

Description: The monoclonal antibody AT130-2 reacts with mouse CD32b, also known as Fc-gamma receptor IIb. CD32b is the only inhibitory member of the Fc-gamma receptor family. Immune complex engagement of CD32b results in the phosphorylation of its intracellular ITIM motif. This engagement serves to attenuate B cell receptor (BCR) signaling and other activating signals, reduces proliferation, reduces antibody production, and may also deliver apoptotic signals. CD32b is the only Fc-gamma receptor expressed by B cells. CD32b is also expressed on monocytes, dendritic cells, neutrophils, eosinophils and basophils, as well as B cell progenitors and plasma cells.AT130-2 has been reported to have agonist activity.Applications Reported: This AT130-2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This AT130-2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD32b
Monoclonal
0.2mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P08101
Fc gamma Receptor II-b, CD32 receptor 2b, CD32, FCG2, FCGR2, IGFR2, CDw32, Fc fragment of IgG, low affinity II, receptor for CD32, Fc gamma RIIb, fc-gamma RII-b, fc-gamma-RIIb, fcRII-b, igG Fc receptor II-b, FGFR2B
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
AT130-2
APC
Fcgr2b
Conjugated
Fcgr2b
IgG2a, kappa
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
14130
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