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CD32b Mouse anti-Mouse, APC, Clone: AT130-2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-0321-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15597906

  • £182.82 / 100µg


Estimated Shipment date
from Supplier 03-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody AT130-2 reacts with mouse CD32b, also known as Fc-gamma receptor IIb. CD32b is the only inhibitory member of the Fc-gamma receptor family. Immune complex engagement of CD32b results in the phosphorylation of its intracellular ITIM motif. This engagement serves to attenuate B cell receptor (BCR) signaling and other activating signals, reduces proliferation, reduces antibody production, and may also deliver apoptotic signals. CD32b is the only Fc-gamma receptor expressed by B cells. CD32b is also expressed on monocytes, dendritic cells, neutrophils, eosinophils and basophils, as well as B cell progenitors and plasma cells.

AT130-2 has been reported to have agonist activity.
Description & Specifications

Specifications

CD32b
AT130-2
Allophycocyanin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
Conjugated
FcRII-b
IgG2a
RUO
Primary
Murine