CD32b, APC, clone: AT130-2, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-0321-80
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: The monoclonal antibody AT130-2 reacts with mouse CD32b, also known as Fc-gamma receptor IIb. CD32b is the only inhibitory member of the Fc-gamma receptor family. Immune complex engagement of CD32b results in the phosphorylation of its intracellular ITIM motif. This engagement serves to attenuate B cell receptor (BCR) signaling and other activating signals, reduces proliferation, reduces antibody production, and may also deliver apoptotic signals. CD32b is the only Fc-gamma receptor expressed by B cells. CD32b is also expressed on monocytes, dendritic cells, neutrophils, eosinophils and basophils, as well as B cell progenitors and plasma cells.AT130-2 has been reported to have agonist activity.Applications Reported: This AT130-2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This AT130-2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Fc gamma Receptor II-b, CD32 receptor 2b, CD32, FCG2, FCGR2, IGFR2, CDw32, Fc fragment of IgG, low affinity II, receptor for CD32, Fc gamma RIIb, fc-gamma RII-b, fc-gamma-RIIb, fcRII-b, igG Fc receptor II-b, FGFR2B|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.