missing translation for 'onlineSavingsMsg'
Learn More

CD326 (EpCAM) Rat anti-Mouse, eFluor 450, Clone: G8.8, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-5791-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15351790

  • £176.70 / 100µg


EU Stock 2
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The G8.8 monoclonal antibody reacts with the 40kDa protein mouse EpCAM (epithelial cellular adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326. The immunogen used to generate the G8.8 antibody was the TE-71 thymic epithelial cell line. CD326 is expressed on the majority of epithelial cells, and is considered a pan-carcinoma antigen. CD326 mediates calcium-independent, homophilic, cell-cell adhesion and may function as a growth factor receptor. The antigen is being used as a target for immunotherapy treatment of human carcinomas. CD326 binds LAIR-1 (CD305) and LAIR-2 (CD306) to inhibit cellular activation and inflammation. This epithelial glycoprotein is now recognized as having an important role in tumor biology.
Specifications

Specifications

CD326 (EpCAM)
G8.8
eFluor 450
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
epithelial cell adhesion molecule
IgG2a
RUO
Primary
Murine