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CD326 (EpCAM) Rat anti-Mouse, APC-eFluor 780, Clone: G8.8, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 47-5791-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15589586

  • £188.93 / 100µg


EU Stock 5
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Disclaimers:

For Research Use Only.


Description

Description

The G8.8 monoclonal antibody reacts with the 40kDa protein mouse EpCAM (epithelial cellular adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326. The immunogen used to generate the G8.8 antibody was the TE-71 thymic epithelial cell line. CD326 is expressed on the majority of epithelial cells, and is considered a pan-carcinoma antigen. CD326 mediates calcium-independent, homophilic, cell-cell adhesion and may function as a growth factor receptor. The antigen is being used as a target for immunotherapy treatment of human carcinomas. CD326 binds LAIR-1 (CD305) and LAIR-2 (CD306) to inhibit cellular activation and inflammation. This epithelial glycoprotein is now recognized as having an important role in tumor biology.
Specifications

Specifications

CD326 (EpCAM)
G8.8
APC-eFluor 780
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
epithelial cell adhesion molecule
IgG2a
RUO
Primary
Murine