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CD325 (N-Cadherin), PE, clone: 8C11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-3259-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15556966

  • £68.33 / 25 tests


Estimated Shipment date
from Supplier 27-06-2018
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Description

Description

Description: The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin. CD325 is a 130kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells.Applications Reported: This 8C11 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 8C11 antibody has been pre-titrated and tested by flow cytometric analysis of HeLa cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD325 (N-cadherin)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P19022
Cadherin-2, Neural-cadherin, CDw325 antigen, CD325, CDHN, NCAD, Cadherin-N
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
8C11
PE
CDH2
Conjugated
CDH2
IgG1, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
1000
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