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CD325 (N-cadherin) Mouse anti-Human, Clone: 8C11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-3259-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15207347

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Disclaimers:

For Research Use Only.


Description

Description

The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin. CD325 is a 130kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells.
Specifications

Specifications

CD325 (N-cadherin)
8C11
Unconjugated
Purified
Murine
25μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
neural cadherin
IgG1
RUO
Primary
Human
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