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CD325 (N-Cadherin) Monoclonal Antibody (8C11), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£94.25 - £246.00

Specifications

Antigen CD325 (N-Cadherin)
Clone 8C11
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
15508086
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Affymetrix eBioscience
17-3259-42
100 Tests
£246.00
100 tests
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15598076
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Affymetrix eBioscience
17-3259-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin. CD325 is a 130 kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells. Applications Reported: This 8C11 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 8C11 antibody has been pre-titrated and tested by flow cytometric analysis of the HeLa cell line. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD325 (N-Cadherin) Monoclonal antibody specifically detects CD325 (N-Cadherin) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD325 (N-Cadherin)
5 μL/Test
Monoclonal
Liquid
RUO
P19022
CDH2
Primary
4° C, store in dark, DO NOT FREEZE!
CDH2
8C11
Flow Cytometry
APC
Mouse
Human
1000
IgG1 κ
Affinity chromatography
Antibody
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