CD325 (N-cadherin) Mouse anti-Human, APC, Clone: 8C11, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-3259-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15598076

Quantity Price
1 £ 84.99 / 25 tests
EU Stock 1
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Description and Specification

Specification

Isotype IgG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 8C11
Regulatory Status RUO
Format Conjugated
Antigen CD325 (N-cadherin)
Conjugate APC
Gene Alias neural cadherin
Primary or Secondary Primary
Applications Flow Cytometry
Species Reactivity Human
Host Species Mouse
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal
Concentration 5μL (0.25μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin. CD325 is a 130kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells.