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CD321 (F11R) Monoclonal Antibody (CSTEM27), eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£78.25 - £120.00
Specifications
Antigen | CD321 (F11R) |
---|---|
Clone | CSTEM27 |
Concentration | 0.5 mg/mL |
Classification | Monoclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15805353
|
Affymetrix eBioscience
14-3219-82 |
100 μg |
£120.00
100µg |
Estimated Shipment: 13-05-2024 Log in to see stock. |
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15895343
|
Affymetrix eBioscience
14-3219-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
This monoclonal antibody CSTEM27 reacts with human CD321 (F11R, JAM-1, JAM-A). Applications Reported: This CSTEM27 antibody has been reported for use in immunocytochemical staining, flow cytometric analysis, and western blot. (Fluorochrome-conjugated CSTEM27 is recommended for use in flow cytometery.) Applications Tested: This CSTEM27 antibody has been tested by immunocytochemistry of adherent cells. This can be used at less than or equal to 5 μg/mL. This CSTEM27 antibody has also been tested by flow cytometric analysis of human iPSCs. This may be used at 0.25 μg/test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.Specifications
CD321 (F11R) | |
0.5 mg/mL | |
Unconjugated | |
Mouse | |
Human | |
50848 | |
Primary | |
4° C, do not freeze |
CSTEM27 | |
Monoclonal | |
Liquid | |
RUO | |
Q9Y624 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |