CD321 (F11R) Mouse anti-Human, Clone: WK9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9321-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15228167

Quantity Price
1 £ 121.67 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Conjugate Unlabeled
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Format Purified
Gene Alias F11 R, JAM-1, JAM-A
Regulatory Status RUO
Primary or Secondary Primary
Isotype IgG1
Clone WK9
Quantity 100μg
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Antigen CD321 (F11R)

CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is also involved in reovirus entry into cells.