CD32 Mouse anti-Human, PE, Clone: 6C4 (CD32), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0329-42

100TEST Anti-Human CD32 PE

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15556756

Quantity Price
1 £ 170.59 / 100 tests
Estimated Shipment date
from Supplier 31-03-2017
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Description and Specification

Specification

Applications Flow Cytometry
Format Conjugated
Isotype IgG1
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD32
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Host Species Mouse
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone 6C4 (CD32)
Concentration 5μL (0.125μg)/test
Conjugate PE
Quantity 100 tests

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gamma RII). This antibody recognizes two isoforms of the receptor, Fc gamma RIIA and Fc gamma RIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gamma RII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.