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CD32 Mouse anti-Human, eFluor 450, Clone: 6C4 (CD32), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-0329-41

Code : NEW

Additional Details : Weight : 0.23750kg

Product Code. 15589656

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Description

Description

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.
Specifications

Specifications

CD32
Monoclonal
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Mouse
RUO
Human
IgG1 κ
Flow Cytometry
6C4 (CD32)
eFluor 450
Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
25 Tests
Primary
Store at 2-8°C. Do not freeze. Light-sensitive material.
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