CD32 Mouse anti-Human, Clone: 6C4 (CD32), Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0329-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15278427

Quantity Price
1 £ 213.39 / 500µg
EU Stock 12
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Description and Specification

Specification

Applications Functional Assay
Formulation aqueous buffer, no sodium azide
Quantity 500μg
Format Purified
Conjugate Unlabeled
Antigen CD32
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Species Reactivity Human
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Concentration 1mg/mL
Isotype IgG1
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Clone 6C4 (CD32)

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.