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CD32 Mouse anti-Human, Clone: 6C4 (CD32), Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-0329-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15268427

  • £66.65 / 50µg


Estimated Shipment
08-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.
Description & Specifications

Specifications

CD32
6C4 (CD32)
Unlabeled
aqueous buffer, no sodium azide
Murine
50μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
Purified
Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
IgG1
RUO
Primary
Human